GO Annotations Graph

• Symbol: Enpp3
• Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
• ID: MGI:2143702

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	ISO	J:164563
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	IMP	J:223825
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	IBA	J:265628
Molecular Function	GO:0004528	phosphodiesterase I activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:223825
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0046034	ATP metabolic process	IMP	J:223825
Biological Process	GO:0046034	ATP metabolic process	ISO	J:164563
Biological Process	GO:0002276	basophil activation involved in immune response	IMP	J:223825
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:223825
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	IMP	J:223825
Biological Process	GO:0070667	negative regulation of mast cell proliferation	IMP	J:223825
Biological Process	GO:0009143	nucleoside triphosphate catabolic process	ISO	J:164563
Biological Process	GO:0009143	nucleoside triphosphate catabolic process	IBA	J:265628
Biological Process	GO:0055062	phosphate ion homeostasis	IDA	J:173773
Biological Process	GO:0006796	phosphate-containing compound metabolic process	ISO	J:164563
Biological Process	GO:0006220	pyrimidine nucleotide metabolic process	ISO	J:164563