GO Annotations Graph

• Symbol: Xpo1
• Name: exportin 1
• ID: MGI:2144013

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0005049	nuclear export signal receptor activity	ISO	J:164563
Molecular Function	GO:0005049	nuclear export signal receptor activity	IMP	J:285490
Molecular Function	GO:0005049	nuclear export signal receptor activity	IBA	J:265628
Molecular Function	GO:0005049	nuclear export signal receptor activity	IMP	J:80612
Molecular Function	GO:0005049	nuclear export signal receptor activity	IDA	J:285490
Molecular Function	GO:0005049	nuclear export signal receptor activity	IDA	J:80612
Molecular Function	GO:0005515	protein binding	IPI	J:247413
Molecular Function	GO:0005515	protein binding	IPI	J:196265
Molecular Function	GO:0005515	protein binding	IPI	J:222157
Molecular Function	GO:0005515	protein binding	IPI	J:248238
Molecular Function	GO:0005515	protein binding	IPI	J:247411
Molecular Function	GO:0005515	protein binding	IPI	J:231233
Molecular Function	GO:0005515	protein binding	IPI	J:97559
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0031267	small GTPase binding	IEA	J:72247
Cellular Component	GO:0005642	annulate lamellae	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:103773
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:142821
Biological Process	GO:0006886	intracellular protein transport	IEA	J:72247
Biological Process	GO:0006406	mRNA export from nucleus	IMP	J:285490
Biological Process	GO:0006406	mRNA export from nucleus	IDA	J:285490
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0006913	nucleocytoplasmic transport	ISO	J:164563
Biological Process	GO:0006611	protein export from nucleus	ISO	J:155856
Biological Process	GO:0006611	protein export from nucleus	IDA	J:142024
Biological Process	GO:0006611	protein export from nucleus	IMP	J:103171
Biological Process	GO:0006611	protein export from nucleus	IDA	J:75684
Biological Process	GO:0006611	protein export from nucleus	IMP	J:106641
Biological Process	GO:0006611	protein export from nucleus	IMP	J:107024
Biological Process	GO:0006611	protein export from nucleus	IMP	J:97559
Biological Process	GO:0006611	protein export from nucleus	IDA	J:80612
Biological Process	GO:0006611	protein export from nucleus	IMP	J:137074
Biological Process	GO:0006611	protein export from nucleus	ISO	J:73065
Biological Process	GO:0006611	protein export from nucleus	IMP	J:154728
Biological Process	GO:0006611	protein export from nucleus	IMP	J:148303
Biological Process	GO:0006611	protein export from nucleus	IMP	J:153534
Biological Process	GO:0006611	protein export from nucleus	IMP	J:105832
Biological Process	GO:0034504	protein localization to nucleus	IMP	J:103773
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0010824	regulation of centrosome duplication	IMP	J:103773
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0042176	regulation of protein catabolic process	IMP	J:97559
Biological Process	GO:0046825	regulation of protein export from nucleus	IMP	J:88659
Biological Process	GO:0000055	ribosomal large subunit export from nucleus	ISO	J:164563
Biological Process	GO:0000055	ribosomal large subunit export from nucleus	IBA	J:265628
Biological Process	GO:0000056	ribosomal small subunit export from nucleus	ISO	J:164563
Biological Process	GO:0000056	ribosomal small subunit export from nucleus	IBA	J:265628
Biological Process	GO:0000054	ribosomal subunit export from nucleus	ISO	J:164563
Biological Process	GO:0042254	ribosome biogenesis	ISO	J:164563