GO Annotations Graph

• Symbol: Fbxw11
• Name: F-box and WD-40 domain protein 11
• ID: MGI:2144023

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070840	dynein complex binding	IBA	J:265628
Molecular Function	GO:0051010	microtubule plus-end binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:75267
Molecular Function	GO:0005515	protein binding	IPI	J:166433
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:75267
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IDA	J:75267
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TAS	Reactome:R-NUL-5610711
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:228114
Cellular Component	GO:0005737	cytoplasm	IDA	J:75267
Cellular Component	GO:0005881	cytoplasmic microtubule	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:166433
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-5610711
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0005875	microtubule associated complex	IBA	J:265628
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:166433
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	IDA	J:75267
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	ISO	J:164563
Biological Process	GO:0048854	brain morphogenesis	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0000132	establishment of mitotic spindle orientation	IBA	J:265628
Biological Process	GO:0007281	germ cell development	IBA	J:265628
Biological Process	GO:0031023	microtubule organizing center organization	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	IMP	J:75267
Biological Process	GO:0007097	nuclear migration	IBA	J:265628
Biological Process	GO:0042753	positive regulation of circadian rhythm	IMP	J:166433
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:166433
Biological Process	GO:0045862	positive regulation of proteolysis	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	IDA	J:166433
Biological Process	GO:0031648	protein destabilization	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	IDA	J:75267
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0008090	retrograde axonal transport	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IMP	J:75267
Biological Process	GO:0047496	vesicle transport along microtubule	IBA	J:265628
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000