GO Annotations Graph

• Symbol: Arhgap44
• Name: Rho GTPase activating protein 44
• ID: MGI:2144423

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	IDA	J:213034
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	IPI	J:213034
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:213034
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:198646
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:198646
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:198646
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:198646
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:198646
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:198646
Cellular Component	GO:0005622	intracellular anatomical structure	IBA	J:265628
Cellular Component	GO:0031256	leading edge membrane	ISO	J:164563
Cellular Component	GO:0031256	leading edge membrane	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:155856
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:155856
Cellular Component	GO:0048786	presynaptic active zone	IBA	J:265628
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0098886	modification of dendritic spine	IMP	J:198646
Biological Process	GO:0098886	modification of dendritic spine	IBA	J:265628
Biological Process	GO:0099010	modification of postsynaptic structure	IDA	J:198646
Biological Process	GO:0099010	modification of postsynaptic structure	IDA	J:198646
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:198646
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:198646
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:198646
Biological Process	GO:0051490	negative regulation of filopodium assembly	ISO	J:155856
Biological Process	GO:0035021	negative regulation of Rac protein signal transduction	IMP	J:213034
Biological Process	GO:0035021	negative regulation of Rac protein signal transduction	IBA	J:265628
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	IMP	J:198646
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	IBA	J:265628
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IMP	J:238439
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	IMP	J:213034
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0043087	regulation of GTPase activity	IDA	J:213034
Biological Process	GO:0099152	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	IDA	J:198646
Biological Process	GO:0099152	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	IDA	J:198646
Biological Process	GO:0099152	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	IMP	J:198646
Biological Process	GO:0007165	signal transduction	IEA	J:72247