GO Annotations Graph

• Symbol: Pik3r6
• Name: phosphoinositide-3-kinase regulatory subunit 5
• ID: MGI:2144613

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	IDA	J:97091
Molecular Function	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	IBA	J:265628
Molecular Function	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	IDA	J:155302
Molecular Function	GO:0005515	protein binding	IPI	J:173562
Molecular Function	GO:0005515	protein binding	IPI	J:97091
Molecular Function	GO:0005515	protein binding	IPI	J:201418
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0016020	membrane	IDA	J:155302
Cellular Component	GO:0005942	phosphatidylinositol 3-kinase complex	IBA	J:265628
Cellular Component	GO:0005943	phosphatidylinositol 3-kinase complex, class IA	ISO	J:164563
Cellular Component	GO:0005944	phosphatidylinositol 3-kinase complex, class IB	IDA	J:97091
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:155302
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IDA	J:155302
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IBA	J:265628
Biological Process	GO:0045582	positive regulation of T cell differentiation	IMP	J:110820
Biological Process	GO:0042269	regulation of natural killer cell mediated cytotoxicity	ISO	J:164563