GO Annotations Graph

• Symbol: Ddx1
• Name: DEAD box helicase 1
• ID: MGI:2144727

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0033677	DNA/RNA helicase activity	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	IDA	J:173994
Molecular Function	GO:0004527	exonuclease activity	IEA	J:60000
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0008143	poly(A) binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:166012
Molecular Function	GO:0005515	protein binding	IPI	J:173994
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003724	RNA helicase activity	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Cellular Component	GO:0071920	cleavage body	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:177884
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:173994
Cellular Component	GO:0005739	mitochondrion	IDA	J:173994
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:142821
Cellular Component	GO:0072669	tRNA-splicing ligase complex	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0032508	DNA duplex unwinding	ISO	J:164563
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:173994
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	IMP	J:173994
Biological Process	GO:1903608	protein localization to cytoplasmic stress granule	ISO	J:164563
Biological Process	GO:0043330	response to exogenous dsRNA	IMP	J:173994
Biological Process	GO:0009615	response to virus	IMP	J:173994
Biological Process	GO:0008033	tRNA processing	IEA	J:60000
Biological Process	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	ISO	J:164563