GO Annotations Graph

• Symbol: Ptpn23
• Name: protein tyrosine phosphatase, non-receptor type 23
• ID: MGI:2144837

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:201308
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0036064	ciliary basal body	ISO	J:164563
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0060271	cilium assembly	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0045022	early endosome to late endosome transport	IBA	J:265628
Biological Process	GO:0032456	endocytic recycling	ISO	J:164563
Biological Process	GO:0032456	endocytic recycling	IBA	J:265628
Biological Process	GO:0071985	multivesicular body sorting pathway	IEA	J:72247
Biological Process	GO:0010633	negative regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:1903393	positive regulation of adherens junction organization	ISO	J:164563
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:1903387	positive regulation of homophilic cell adhesion	ISO	J:164563
Biological Process	GO:0061357	positive regulation of Wnt protein secretion	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	IEA	J:72247
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0043328	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IBA	J:265628
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563