GO Annotations Graph

• Symbol: Nhlrc1
• Name: NHL repeat containing 1
• ID: MGI:2145264

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:125489
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0030371	translation repressor activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:125489
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:322978
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:125489
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:125489
Biological Process	GO:0006914	autophagy	IMP	J:216005
Biological Process	GO:0005978	glycogen biosynthetic process	IMP	J:165994
Biological Process	GO:0005978	glycogen biosynthetic process	IMP	J:274435
Biological Process	GO:0005978	glycogen biosynthetic process	IGI	J:262451
Biological Process	GO:0005977	glycogen metabolic process	IMP	J:199271
Biological Process	GO:0005977	glycogen metabolic process	IMP	J:217884
Biological Process	GO:0005977	glycogen metabolic process	IMP	J:216005
Biological Process	GO:0043170	macromolecule metabolic process	IMP	J:199271
Biological Process	GO:0017148	negative regulation of translation	IBA	J:265628
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IDA	J:125489
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	J:216005
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0000209	protein polyubiquitination	IBA	J:265628
Biological Process	GO:0016567	protein ubiquitination	IDA	J:125489
Biological Process	GO:0010468	regulation of gene expression	IMP	J:216005
Biological Process	GO:0045859	regulation of protein kinase activity	IMP	J:216005
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	IGI	J:255653
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:216005
Biological Process	GO:0031396	regulation of protein ubiquitination	IGI	J:255653
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:150197
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:322978