Ppif GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ppif
peptidylprolyl isomerase F (cyclophilin F)
MGI:2145814

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016018	cyclosporin A binding	ISO	J:164563
Molecular Function	GO:0016018	cyclosporin A binding	ISO	J:155856
Molecular Function	GO:0016018	cyclosporin A binding	IBA	J:265628
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0042277	peptide binding	ISO	J:155856
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	ISO	J:164563
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	ISO	J:155856
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	TAS	J:180458
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:296126
Molecular Function	GO:0005515	protein binding	IPI	J:186254
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:155856
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	ISO	J:164563
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	IMP	J:287067
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	TAS	J:180458
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Biological Process	GO:0008637	apoptotic mitochondrial changes	IGI	J:133172
Biological Process	GO:0008637	apoptotic mitochondrial changes	IGI	J:133172
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0071243	cellular response to arsenic-containing substance	IMP	J:196258
Biological Process	GO:0071277	cellular response to calcium ion	IMP	J:97673
Biological Process	GO:0071277	cellular response to calcium ion	IMP	J:97660
Biological Process	GO:0071277	cellular response to calcium ion	IMP	J:101149
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IMP	J:97673
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IMP	J:101149
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IMP	J:97660
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IMP	J:186254
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IBA	J:265628
Biological Process	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	ISO	J:164563
Biological Process	GO:0070266	necroptotic process	IGI	J:186254
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	IMP	J:196258
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0090324	negative regulation of oxidative phosphorylation	IMP	J:196258
Biological Process	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity	IMP	J:196258
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	IMP	J:97660
Biological Process	GO:0012501	programmed cell death	IEA	J:60000
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0000413	protein peptidyl-prolyl isomerization	TAS	J:180458
Biological Process	GO:0000413	protein peptidyl-prolyl isomerization	ISO	J:164563
Biological Process	GO:0000413	protein peptidyl-prolyl isomerization	IBA	J:265628
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IMP	J:196093
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	ISO	J:155856
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IMP	J:101149
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	ISO	J:164563
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IMP	J:287067
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IGI	J:186254
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	IMP	J:101149
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	ISO	J:164563
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	IMP	J:186254
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	IMP	J:97673
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	IBA	J:265628
Biological Process	GO:0010939	regulation of necrotic cell death	IDA	J:97660
Biological Process	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism	IMP	J:196258
Biological Process	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism	IMP	J:196088
Biological Process	GO:0002931	response to ischemia	IMP	J:97673
Biological Process	GO:0002931	response to ischemia	IMP	J:101149
Biological Process	GO:0006979	response to oxidative stress	IGI	J:186254

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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