GO Annotations Graph

• Symbol: Ano6
• Name: anoctamin 6
• ID: MGI:2145890

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005227	calcium activated cation channel activity	ISO	J:164563
Molecular Function	GO:0005227	calcium activated cation channel activity	IDA	J:188263
Molecular Function	GO:0005254	chloride channel activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:196141
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:276401
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IMP	J:203552
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	IDA	J:165954
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017128	phospholipid scramblase activity	ISO	J:164563
Molecular Function	GO:0017128	phospholipid scramblase activity	IDA	J:276401
Molecular Function	GO:0017128	phospholipid scramblase activity	IMP	J:198369
Molecular Function	GO:0017128	phospholipid scramblase activity	IDA	J:198369
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:276401
Molecular Function	GO:0005247	voltage-gated chloride channel activity	ISO	J:164563
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IDA	J:188263
Cellular Component	GO:0034707	chloride channel complex	ISO	J:164563
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:288076
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:288076
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:288076
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:288076
Cellular Component	GO:0098981	cholinergic synapse	IMP	J:288076
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:276401
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0097060	synaptic membrane	IDA	J:288076
Cellular Component	GO:0097060	synaptic membrane	IDA	J:288076
Biological Process	GO:0002543	activation of blood coagulation via clotting cascade	ISO	J:164563
Biological Process	GO:0032060	bleb assembly	IMP	J:220493
Biological Process	GO:0032060	bleb assembly	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	IMP	J:188263
Biological Process	GO:0035630	bone mineralization involved in bone maturation	IMP	J:195901
Biological Process	GO:0061591	calcium activated galactosylceramide scrambling	IDA	J:198369
Biological Process	GO:0061590	calcium activated phosphatidylcholine scrambling	IBA	J:265628
Biological Process	GO:0061590	calcium activated phosphatidylcholine scrambling	IDA	J:198369
Biological Process	GO:0061589	calcium activated phosphatidylserine scrambling	IBA	J:265628
Biological Process	GO:0061589	calcium activated phosphatidylserine scrambling	IDA	J:198369
Biological Process	GO:0061588	calcium activated phospholipid scrambling	IMP	J:198369
Biological Process	GO:0061588	calcium activated phospholipid scrambling	IMP	J:195901
Biological Process	GO:0070588	calcium ion transmembrane transport	IGI	J:220494
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:1902476	chloride transmembrane transport	IDA	J:276401
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:1902476	chloride transmembrane transport	IMP	J:220494
Biological Process	GO:1902476	chloride transmembrane transport	IBA	J:265628
Biological Process	GO:0006821	chloride transport	ISO	J:164563
Biological Process	GO:0006821	chloride transport	IDA	J:165954
Biological Process	GO:0006821	chloride transport	IMP	J:203552
Biological Process	GO:0002407	dendritic cell chemotaxis	IMP	J:203552
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:195901
Biological Process	GO:0051649	establishment of localization in cell	IDA	J:198369
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:198369
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:203552
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0006812	monoatomic cation transport	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0045794	negative regulation of cell volume	ISO	J:164563
Biological Process	GO:0045794	negative regulation of cell volume	IMP	J:220493
Biological Process	GO:0097045	phosphatidylserine exposure on blood platelet	ISO	J:164563
Biological Process	GO:0045332	phospholipid translocation	IDA	J:276401
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	IMP	J:188263
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	ISO	J:164563
Biological Process	GO:0046931	pore complex assembly	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:220493
Biological Process	GO:0030501	positive regulation of bone mineralization	IMP	J:220494
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0034767	positive regulation of monoatomic ion transmembrane transport	IMP	J:220493
Biological Process	GO:0034767	positive regulation of monoatomic ion transmembrane transport	ISO	J:164563
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	ISO	J:164563
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	IMP	J:220493
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	IMP	J:220493
Biological Process	GO:1903766	positive regulation of potassium ion export across plasma membrane	ISO	J:155856
Biological Process	GO:0035590	purinergic nucleotide receptor signaling pathway	ISO	J:164563
Biological Process	GO:0035590	purinergic nucleotide receptor signaling pathway	IMP	J:220493
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IDA	J:288076
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IMP	J:288076
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IDA	J:288076
Biological Process	GO:0035725	sodium ion transmembrane transport	ISO	J:164563