Ticam1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ticam1
TIR domain containing adaptor molecule 1
MGI:2147032

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:162535
Molecular Function	GO:0005515	protein binding	IPI	J:171920
Molecular Function	GO:0005515	protein binding	IPI	J:183537
Molecular Function	GO:0005515	protein binding	IPI	J:169794
Molecular Function	GO:0005515	protein binding	IPI	J:166021
Molecular Function	GO:0005515	protein binding	IPI	J:144594
Molecular Function	GO:0005515	protein binding	IPI	J:245346
Molecular Function	GO:0005515	protein binding	IPI	J:173994
Molecular Function	GO:0005515	protein binding	IPI	J:224712
Molecular Function	GO:0005515	protein binding	IPI	J:152781
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:173994
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:173994
Cellular Component	GO:0097342	ripoptosome	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0097190	apoptotic signaling pathway	IMP	J:84896
Biological Process	GO:0042113	B cell activation	IMP	J:84679
Biological Process	GO:0042100	B cell proliferation	IMP	J:84679
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:123633
Biological Process	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	IMP	J:158401
Biological Process	GO:0032602	chemokine production	IMP	J:84679
Biological Process	GO:0032602	chemokine production	IGI	J:84679
Biological Process	GO:0051607	defense response to virus	IMP	J:84896
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IGI	J:84679
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IMP	J:84679
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:72247
Biological Process	GO:0032608	interferon-beta production	IMP	J:84679
Biological Process	GO:0032608	interferon-beta production	IMP	J:84896
Biological Process	GO:0032635	interleukin-6 production	IMP	J:84679
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IMP	J:84896
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IMP	J:84679
Biological Process	GO:0002281	macrophage activation involved in immune response	IMP	J:84896
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:84679
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:84679
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:84896
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:84896
Biological Process	GO:0010934	macrophage cytokine production	IGI	J:84896
Biological Process	GO:0010934	macrophage cytokine production	IDA	J:84896
Biological Process	GO:0010934	macrophage cytokine production	IMP	J:84679
Biological Process	GO:0002756	MyD88-independent toll-like receptor signaling pathway	IMP	J:84896
Biological Process	GO:0002756	MyD88-independent toll-like receptor signaling pathway	IMP	J:84679
Biological Process	GO:0006809	nitric oxide biosynthetic process	IMP	J:84896
Biological Process	GO:0010508	positive regulation of autophagy	IMP	J:123633
Biological Process	GO:0050871	positive regulation of B cell activation	IMP	J:84679
Biological Process	GO:0030890	positive regulation of B cell proliferation	IMP	J:84679
Biological Process	GO:0032722	positive regulation of chemokine production	IMP	J:84679
Biological Process	GO:0032722	positive regulation of chemokine production	IGI	J:84679
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IMP	J:158401
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:158401
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:158401
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:173994
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:84679
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IGI	J:84679
Biological Process	GO:0032728	positive regulation of interferon-beta production	IMP	J:84679
Biological Process	GO:0032728	positive regulation of interferon-beta production	IMP	J:84896
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:84679
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IGI	J:84896
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:84896
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:84679
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:84679
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IDA	J:84896
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:84679
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:84896
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:84679
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	IMP	J:173994
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	IBA	J:265628
Biological Process	GO:0032816	positive regulation of natural killer cell activation	IBA	J:265628
Biological Process	GO:0032816	positive regulation of natural killer cell activation	IMP	J:177021
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IBA	J:265628
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IGI	J:84679
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IMP	J:84679
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IMP	J:84896
Biological Process	GO:0032092	positive regulation of protein binding	IDA	J:152781
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IDA	J:152781
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:84896
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IGI	J:84896
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IDA	J:84896
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:84679
Biological Process	GO:0032481	positive regulation of type I interferon production	ISO	J:164563
Biological Process	GO:0032481	positive regulation of type I interferon production	IMP	J:84896
Biological Process	GO:0043254	regulation of protein-containing complex assembly	IMP	J:84896
Biological Process	GO:0043330	response to exogenous dsRNA	IBA	J:265628
Biological Process	GO:0043330	response to exogenous dsRNA	IMP	J:84896
Biological Process	GO:0043330	response to exogenous dsRNA	IMP	J:84679
Biological Process	GO:0043330	response to exogenous dsRNA	ISO	J:170947
Biological Process	GO:0043330	response to exogenous dsRNA	IDA	J:84896
Biological Process	GO:0043330	response to exogenous dsRNA	IMP	J:173994
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:84679
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:84896
Biological Process	GO:0032496	response to lipopolysaccharide	IGI	J:84896
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:84679
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0002224	toll-like receptor signaling pathway	ISO	J:164563
Biological Process	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	ISO	J:164563
Biological Process	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	IMP	J:123633
Biological Process	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	IBA	J:265628
Biological Process	GO:0032640	tumor necrosis factor production	IDA	J:84896
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:84896
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:84679
Biological Process	GO:0032640	tumor necrosis factor production	IGI	J:84896
Biological Process	GO:0032606	type I interferon production	IMP	J:84896

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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