GO Annotations Graph

• Symbol: Lpxn
• Name: leupaxin
• ID: MGI:2147677

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:180575
Molecular Function	GO:0005515	protein binding	IPI	J:180487
Molecular Function	GO:0005515	protein binding	IPI	J:180575
Molecular Function	GO:0005515	protein binding	IPI	J:124931
Molecular Function	GO:0005515	protein binding	IPI	J:180560
Molecular Function	GO:0003712	transcription coregulator activity	IDA	J:182489
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IDA	J:180560
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:182489
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0002102	podosome	IDA	J:180487
Cellular Component	GO:0002102	podosome	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0043542	endothelial cell migration	IBA	J:265628
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	IDA	J:124931
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	IMP	J:180560
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IBA	J:265628
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IBA	J:265628