GO Annotations Graph

• Symbol: Kank1
• Name: KN motif and ankyrin repeat domains 1
• ID: MGI:2147707

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032587	ruffle membrane	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:0030837	negative regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0030837	negative regulation of actin filament polymerization	IBA	J:265628
Biological Process	GO:0030837	negative regulation of actin filament polymerization	ISO	J:133297
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:2000393	negative regulation of lamellipodium morphogenesis	ISO	J:164563
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:1900028	negative regulation of ruffle assembly	ISO	J:164563
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0090521	podocyte cell migration	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:2000114	regulation of establishment of cell polarity	ISO	J:164563
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ISO	J:164563