GO Annotations Graph

• Symbol: Npnt
• Name: nephronectin
• ID: MGI:2148811

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005178	integrin binding	IDA	J:180566
Molecular Function	GO:0005178	integrin binding	IPI	J:72544
Cellular Component	GO:0005604	basement membrane	IDA	J:170886
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IDA	J:170886
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0031012	extracellular matrix	IDA	J:72544
Cellular Component	GO:0031012	extracellular matrix	IDA	J:70545
Cellular Component	GO:0031012	extracellular matrix	IPI	J:70545
Cellular Component	GO:0005576	extracellular region	IDA	J:155528
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0030485	smooth muscle contractile fiber	IDA	J:170886
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:122519
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	IDA	J:180566
Biological Process	GO:0007160	cell-matrix adhesion	IPI	J:70545
Biological Process	GO:0007160	cell-matrix adhesion	IDA	J:72544
Biological Process	GO:0007160	cell-matrix adhesion	IDA	J:70545
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IDA	J:175244
Biological Process	GO:0045184	establishment of protein localization	IMP	J:170886
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:139122
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0097195	pilomotor reflex	IMP	J:170886
Biological Process	GO:0010694	positive regulation of alkaline phosphatase activity	IDA	J:155528
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	IDA	J:139122
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:155528
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IMP	J:175244
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IMP	J:155528
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	IMP	J:170886
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:170886
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IMP	J:122519
Biological Process	GO:0051145	smooth muscle cell differentiation	IDA	J:170886
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IMP	J:122519
Biological Process	GO:0001657	ureteric bud development	IMP	J:122519