GO Annotations Graph

• Symbol: Pawr
• Name: PRKC, apoptosis, WT1, regulator
• ID: MGI:2149961

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0043522	leucine zipper domain binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:113939
Molecular Function	GO:0005515	protein binding	IPI	J:87963
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:155856
Molecular Function	GO:0008157	protein phosphatase 1 binding	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005884	actin filament	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0000785	chromatin	IDA	J:223262
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:87963
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:87963
Cellular Component	GO:0005634	nucleus	IDA	J:113939
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:155856
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:113939
Biological Process	GO:0097190	apoptotic signaling pathway	IGI	J:113939
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	ISO	J:155856
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	ISO	J:155856
Biological Process	GO:0032623	interleukin-2 production	IMP	J:85495
Biological Process	GO:0030889	negative regulation of B cell proliferation	IMP	J:85495
Biological Process	GO:0090281	negative regulation of calcium ion import	ISO	J:155856
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	NAS	J:223262
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:223262
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:223262
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:223262
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:223262
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:223262
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:223262
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:85495
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	IMP	J:85495
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:223262
Biological Process	GO:0045760	positive regulation of action potential	ISO	J:155856
Biological Process	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	IDA	J:87963
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	IBA	J:265628
Biological Process	GO:2000774	positive regulation of cellular senescence	IMP	J:223262
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:223262
Biological Process	GO:0060450	positive regulation of hindgut contraction	ISO	J:155856
Biological Process	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	IMP	J:223262
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	ISO	J:155856
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:1904457	positive regulation of neuronal action potential	ISO	J:155856
Biological Process	GO:2000391	positive regulation of neutrophil extravasation	ISO	J:155856
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	ISO	J:155856
Biological Process	GO:1901082	positive regulation of relaxation of smooth muscle	ISO	J:155856