GO Annotations Graph

• Symbol: Mta1
• Name: metastasis associated 1
• ID: MGI:2150037

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0042826	histone deacetylase binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:319940
Molecular Function	GO:0005515	protein binding	IPI	J:171888
Molecular Function	GO:0005515	protein binding	IPI	J:123470
Molecular Function	GO:0005515	protein binding	IPI	J:319689
Molecular Function	GO:0005515	protein binding	IPI	J:213082
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:106974
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:99777
Molecular Function	GO:0005515	protein binding	IPI	J:106974
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:106974
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0005515	protein binding	IPI	J:76167
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:213082
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:0003713	transcription coactivator activity	IMP	J:212789
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:213082
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:213644
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:99777
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-573373
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-573385
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:71485
Cellular Component	GO:0005634	nucleus	IDA	J:106974
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:99777
Cellular Component	GO:0016581	NuRD complex	ISO	J:164563
Cellular Component	GO:0016581	NuRD complex	NAS	J:319987
Cellular Component	GO:0016581	NuRD complex	IBA	J:265628
Cellular Component	GO:0016581	NuRD complex	IPI	J:106974
Cellular Component	GO:0016581	NuRD complex	IPI	J:106974
Cellular Component	GO:0016581	NuRD complex	IPI	J:106974
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:213082
Biological Process	GO:0006302	double-strand break repair	IMP	J:153679
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0006302	double-strand break repair	IBA	J:265628
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	IMP	J:213082
Biological Process	GO:0040029	epigenetic regulation of gene expression	ISO	J:164563
Biological Process	GO:0016575	histone deacetylation	ISO	J:164563
Biological Process	GO:0016575	histone deacetylation	IBA	J:265628
Biological Process	GO:0045475	locomotor rhythm	IMP	J:213082
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NAS	J:319679
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:156393
Biological Process	GO:1902499	positive regulation of protein autoubiquitination	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0042659	regulation of cell fate specification	NAS	J:319679
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:2000736	regulation of stem cell differentiation	NAS	J:319679
Biological Process	GO:0010212	response to ionizing radiation	IDA	J:153679
Biological Process	GO:0010212	response to ionizing radiation	ISO	J:164563
Biological Process	GO:0010212	response to ionizing radiation	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0033363	secretory granule organization	ISO	J:155856