GO Annotations Graph

• Symbol: Plcz1
• Name: phospholipase C, zeta 1
• ID: MGI:2150308

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004435	phosphatidylinositol phospholipase C activity	IDA	J:88862
Molecular Function	GO:0004435	phosphatidylinositol phospholipase C activity	ISO	J:164563
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	ISO	J:164563
Molecular Function	GO:0004629	phospholipase C activity	IDA	J:77754
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IEA	J:72247
Cellular Component	GO:0005730	nucleolus	IDA	J:257332
Cellular Component	GO:0005654	nucleoplasm	IDA	J:257332
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0045120	pronucleus	IDA	J:257332
Cellular Component	GO:0061827	sperm head	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IDA	J:77754
Biological Process	GO:0007343	egg activation	ISO	J:164563
Biological Process	GO:0007343	egg activation	IDA	J:77754
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	IDA	J:257332
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	ISO	J:164563
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	ISO	J:155856
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007338	single fertilization	IEA	J:60000