GO Annotations Graph

• Symbol: Erc1
• Name: ELKS/RAB6-interacting/CAST family member 1
• ID: MGI:2151013

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:77736
Molecular Function	GO:0031267	small GTPase binding	IDA	J:77736
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IBA	J:265628
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IEP	J:263452
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IDA	J:263452
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IDA	J:263452
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IDA	J:263452
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IDA	J:263452
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IMP	J:263452
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	IDA	J:263452
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0036064	ciliary basal body	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:77736
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0048788	cytoskeleton of presynaptic active zone	IBA	J:265628
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:216293
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:240200
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:240200
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:240200
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0008385	IkappaB kinase complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	ISO	J:155856
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:291188
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:291188
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:291188
Cellular Component	GO:0045202	synapse	IDA	J:201692
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Biological Process	GO:0007252	I-kappaB phosphorylation	ISO	J:164563
Biological Process	GO:0048790	maintenance of presynaptic active zone structure	IBA	J:265628
Biological Process	GO:0007274	neuromuscular synaptic transmission	IBA	J:265628
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:216293
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IMP	J:216293
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:216293
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:216293
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	IDA	J:216293
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	IDA	J:216293
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	IDA	J:216293
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	IMP	J:216293
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	IDA	J:216293
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	IDA	J:216293
Biological Process	GO:0048167	regulation of synaptic plasticity	IBA	J:265628
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	IDA	J:77736
Biological Process	GO:0016082	synaptic vesicle priming	IDA	J:240200
Biological Process	GO:0016082	synaptic vesicle priming	IDA	J:240200
Biological Process	GO:0016082	synaptic vesicle priming	IMP	J:240200