GO Annotations Graph

• Symbol: Ophn1
• Name: oligophrenin 1
• ID: MGI:2151070

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:85384
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0005096	GTPase activator activity	IMP	J:152583
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:179782
Molecular Function	GO:0005515	protein binding	IPI	J:152583
Molecular Function	GO:0005515	protein binding	IPI	J:152583
Cellular Component	GO:0015629	actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:85384
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:179782
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0030425	dendrite	IDA	J:179782
Cellular Component	GO:0043197	dendritic spine	IDA	J:179782
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0043195	terminal bouton	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	IDA	J:152583
Biological Process	GO:0030036	actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0030036	actin cytoskeleton organization	IDA	J:85384
Biological Process	GO:0034329	cell junction assembly	ISO	J:164563
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	ISO	J:164563
Biological Process	GO:0021707	cerebellar granule cell differentiation	ISO	J:164563
Biological Process	GO:0021895	cerebral cortex neuron differentiation	ISO	J:164563
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0045198	establishment of epithelial cell apical/basal polarity	ISO	J:164563
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	ISO	J:155856
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	IDA	J:179782
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0030182	neuron differentiation	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0030100	regulation of endocytosis	IBA	J:265628
Biological Process	GO:0030100	regulation of endocytosis	IMP	J:152583
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ISO	J:164563
Biological Process	GO:0035023	regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	IMP	J:152583
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0048488	synaptic vesicle endocytosis	IBA	J:265628
Biological Process	GO:0048488	synaptic vesicle endocytosis	IGI	J:152583
Biological Process	GO:0048488	synaptic vesicle endocytosis	IMP	J:152583