GO Annotations Graph

• Symbol: Tnfrsf21
• Name: tumor necrosis factor receptor superfamily, member 21
• ID: MGI:2151075

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Cellular Component	GO:0030424	axon	IDA	J:146602
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:109341
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0002250	adaptive immune response	IMP	J:70594
Biological Process	GO:0002250	adaptive immune response	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0007413	axonal fasciculation	ISO	J:155856
Biological Process	GO:0001783	B cell apoptotic process	IMP	J:109341
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0006959	humoral immune response	IMP	J:70594
Biological Process	GO:0006959	humoral immune response	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0042552	myelination	IMP	J:205651
Biological Process	GO:0030889	negative regulation of B cell proliferation	IMP	J:109341
Biological Process	GO:0030889	negative regulation of B cell proliferation	IBA	J:265628
Biological Process	GO:0032693	negative regulation of interleukin-10 production	IMP	J:70594
Biological Process	GO:0032696	negative regulation of interleukin-13 production	IMP	J:70594
Biological Process	GO:0032714	negative regulation of interleukin-5 production	IMP	J:70594
Biological Process	GO:0031642	negative regulation of myelination	ISO	J:164563
Biological Process	GO:0031642	negative regulation of myelination	IBA	J:265628
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:70594
Biological Process	GO:0042130	negative regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:205745
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:146602
Biological Process	GO:0051402	neuron apoptotic process	IBA	J:265628
Biological Process	GO:0097252	oligodendrocyte apoptotic process	IMP	J:205651
Biological Process	GO:0097252	oligodendrocyte apoptotic process	IBA	J:265628
Biological Process	GO:0048713	regulation of oligodendrocyte differentiation	IMP	J:205651
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:70594