GO Annotations Graph

• Symbol: Dgcr8
• Name: DGCR8, microprocessor complex subunit
• ID: MGI:2151114

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	IBA	J:265628
Molecular Function	GO:0020037	heme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0070878	primary miRNA binding	ISO	J:164563
Molecular Function	GO:0070878	primary miRNA binding	IBA	J:265628
Molecular Function	GO:0070878	primary miRNA binding	IDA	J:258363
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0140517	protein-RNA adaptor activity	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:190566
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:190566
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:190566
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:190566
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:190566
Cellular Component	GO:0070877	microprocessor complex	ISO	J:164563
Cellular Component	GO:0070877	microprocessor complex	IBA	J:265628
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9022302
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0014069	postsynaptic density	IDA	J:190566
Cellular Component	GO:0014069	postsynaptic density	IPI	J:190566
Cellular Component	GO:0014069	postsynaptic density	IPI	J:190566
Cellular Component	GO:0014069	postsynaptic density	IEP	J:190566
Cellular Component	GO:0014069	postsynaptic density	IDA	J:190566
Cellular Component	GO:0014069	postsynaptic density	IDA	J:190566
Biological Process	GO:2000633	positive regulation of pre-miRNA processing	ISO	J:164563
Biological Process	GO:0031053	primary miRNA processing	IBA	J:265628
Biological Process	GO:0031053	primary miRNA processing	ISO	J:73065
Biological Process	GO:0072091	regulation of stem cell proliferation	IMP	J:173330