GO Annotations Graph

• Symbol: Synpo2
• Name: synaptopodin 2
• ID: MGI:2153070

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	IDA	J:128983
Molecular Function	GO:0003779	actin binding	IBA	J:265628
Molecular Function	GO:0003779	actin binding	ISA	J:72383
Molecular Function	GO:0051393	alpha-actinin binding	ISO	J:164563
Molecular Function	GO:0031005	filamin binding	ISO	J:164563
Molecular Function	GO:0051371	muscle alpha-actinin binding	IDA	J:128983
Molecular Function	GO:0005515	protein binding	IPI	J:128983
Molecular Function	GO:0005515	protein binding	IPI	J:128983
Molecular Function	GO:0005515	protein binding	IPI	J:99660
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:128983
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0001725	stress fiber	ISO	J:155856
Cellular Component	GO:0001725	stress fiber	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	IBA	J:265628
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Cellular Component	GO:0030018	Z disc	ISO	J:164563
Cellular Component	GO:0030018	Z disc	IBA	J:265628
Cellular Component	GO:0030018	Z disc	ISA	J:72383
Biological Process	GO:0000045	autophagosome assembly	ISO	J:155856
Biological Process	GO:0061684	chaperone-mediated autophagy	ISO	J:155856
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	IBA	J:265628
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity	ISO	J:164563