GO Annotations Graph

• Symbol: Trim37
• Name: tripartite motif-containing 37
• ID: MGI:2153072

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:202816
Molecular Function	GO:0140862	histone H2AK119 ubiquitin ligase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	ISO	J:164563
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IBA	J:265628
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0016235	aggresome	ISO	J:164563
Cellular Component	GO:0016235	aggresome	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0035098	ESC/E(Z) complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	IBA	J:265628
Biological Process	GO:0070842	aggresome assembly	ISO	J:164563
Biological Process	GO:0036353	histone H2A-K119 monoubiquitination	IBA	J:265628
Biological Process	GO:0046600	negative regulation of centriole replication	ISO	J:164563
Biological Process	GO:0046600	negative regulation of centriole replication	IBA	J:265628
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	ISO	J:164563
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	IMP	J:217377
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IBA	J:265628
Biological Process	GO:0051865	protein autoubiquitination	ISO	J:164563
Biological Process	GO:0051865	protein autoubiquitination	IBA	J:265628
Biological Process	GO:0016558	protein import into peroxisome matrix	ISO	J:164563
Biological Process	GO:0006513	protein monoubiquitination	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	IEA	J:72247