GO Annotations Graph

• Symbol: Dmbx1
• Name: diencephalon/mesencephalon homeobox 1
• ID: MGI:2153518

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:78146
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:78146
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:99788
Molecular Function	GO:0042802	identical protein binding	IPI	J:99788
Molecular Function	GO:0005515	protein binding	IPI	J:99788
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:99788
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:99788
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IC	J:78146
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:99788
Biological Process	GO:0008343	adult feeding behavior	IGI	J:125193
Biological Process	GO:0008343	adult feeding behavior	IMP	J:125193
Biological Process	GO:0008343	adult feeding behavior	IGI	J:125193
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:125193
Biological Process	GO:0007420	brain development	IEP	J:92785
Biological Process	GO:0007417	central nervous system development	IEP	J:78146
Biological Process	GO:0048589	developmental growth	IEP	J:92785
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:99788
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:78146
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:99788
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:99788
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628