GO Annotations Graph

• Symbol: Sp7
• Name: Sp7 transcription factor 7
• ID: MGI:2153568

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0017151	DEAD/H-box RNA helicase binding	IPI	J:180464
Molecular Function	GO:0003677	DNA binding	IDA	J:74344
Molecular Function	GO:0003677	DNA binding	ISS	J:97532
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:100640
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:266247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:156025
Molecular Function	GO:0005515	protein binding	IPI	J:156025
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:100640
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:191431
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8939880
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:74344
Biological Process	GO:0071529	cementum mineralization	IGI	J:279653
Biological Process	GO:0071529	cementum mineralization	IMP	J:279653
Biological Process	GO:0071529	cementum mineralization	IMP	J:279653
Biological Process	GO:0071529	cementum mineralization	IGI	J:279653
Biological Process	GO:0071529	cementum mineralization	IDA	J:279653
Biological Process	GO:0071529	cementum mineralization	IMP	J:279653
Biological Process	GO:0071344	diphosphate metabolic process	IMP	J:279653
Biological Process	GO:0010467	gene expression	IMP	J:279653
Biological Process	GO:0010467	gene expression	IMP	J:279653
Biological Process	GO:0010467	gene expression	IDA	J:279653
Biological Process	GO:0060218	hematopoietic stem cell differentiation	ISO	J:164563
Biological Process	GO:0001649	osteoblast differentiation	ISO	J:164563
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:74344
Biological Process	GO:2000738	positive regulation of stem cell differentiation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:100640
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:266247
Biological Process	GO:0051336	regulation of hydrolase activity	IMP	J:279653
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:74344