GO Annotations Graph

• Symbol: Plxnb3
• Name: plexin B3
• ID: MGI:2154240

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0098632	cell-cell adhesion mediator activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:196252
Molecular Function	GO:0005515	protein binding	IPI	J:204642
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0051022	Rho GDP-dissociation inhibitor binding	IPI	J:204642
Molecular Function	GO:0017154	semaphorin receptor activity	ISO	J:164563
Molecular Function	GO:0017154	semaphorin receptor activity	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0002116	semaphorin receptor complex	IBA	J:265628
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:164563
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0007162	negative regulation of cell adhesion	IBA	J:265628
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:155856
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	IBA	J:265628
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0010593	negative regulation of lamellipodium assembly	ISO	J:155856
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0050918	positive chemotaxis	ISO	J:164563
Biological Process	GO:0050772	positive regulation of axonogenesis	IBA	J:265628
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	ISO	J:155856
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	ISO	J:164563
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:72247