GO Annotations Graph

• Symbol: Ttbk2
• Name: tau tubulin kinase 2
• ID: MGI:2155779

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019894	kinesin binding	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IMP	J:173629
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IMP	J:197579
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IMP	J:173629
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IMP	J:173629
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:68153
Cellular Component	GO:0005814	centriole	ISO	J:164563
Cellular Component	GO:0005814	centriole	IDA	J:255486
Cellular Component	GO:0005814	centriole	IDA	J:197579
Cellular Component	GO:0005814	centriole	IDA	J:206657
Cellular Component	GO:0036064	ciliary basal body	IDA	J:197579
Cellular Component	GO:0036064	ciliary basal body	IBA	J:265628
Cellular Component	GO:0097546	ciliary base	IDA	J:255486
Cellular Component	GO:0035869	ciliary transition zone	ISO	J:164563
Cellular Component	GO:0035869	ciliary transition zone	IBA	J:265628
Cellular Component	GO:0035869	ciliary transition zone	IDA	J:255486
Cellular Component	GO:0035869	ciliary transition zone	IDA	J:197579
Cellular Component	GO:0035869	ciliary transition zone	IDA	J:197579
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0021681	cerebellar granular layer development	IMP	J:227522
Biological Process	GO:0021935	cerebellar granule cell precursor tangential migration	IMP	J:227522
Biological Process	GO:0021549	cerebellum development	IMP	J:227522
Biological Process	GO:0060271	cilium assembly	IMP	J:197579
Biological Process	GO:0060271	cilium assembly	ISO	J:164563
Biological Process	GO:0060271	cilium assembly	IBA	J:265628
Biological Process	GO:1990403	embryonic brain development	IMP	J:173629
Biological Process	GO:0042733	embryonic digit morphogenesis	IMP	J:197579
Biological Process	GO:0030900	forebrain development	IMP	J:197579
Biological Process	GO:0000226	microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:1904527	negative regulation of microtubule binding	ISO	J:164563
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	ISO	J:164563
Biological Process	GO:1903828	negative regulation of protein localization	IMP	J:197579
Biological Process	GO:1902817	negative regulation of protein localization to microtubule	ISO	J:164563
Biological Process	GO:0021915	neural tube development	IMP	J:197579
Biological Process	GO:0018105	peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IDA	J:68153
Biological Process	GO:1902857	positive regulation of non-motile cilium assembly	IMP	J:197579
Biological Process	GO:0008104	protein localization	IMP	J:197579
Biological Process	GO:0033365	protein localization to organelle	IMP	J:255486
Biological Process	GO:0033365	protein localization to organelle	IMP	J:255486
Biological Process	GO:0030334	regulation of cell migration	ISO	J:164563
Biological Process	GO:0008589	regulation of smoothened signaling pathway	IMP	J:197579
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0007224	smoothened signaling pathway	IMP	J:197579