GO Annotations Graph

• Symbol: Rrm2b
• Name: ribonucleotide reductase M2 B (TP53 inducible)
• ID: MGI:2155865

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IBA	J:265628
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IDA	J:72397
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IC	J:122389
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0009265	2'-deoxyribonucleotide biosynthetic process	ISO	J:164563
Biological Process	GO:0009200	deoxyribonucleoside triphosphate metabolic process	IMP	J:84841
Biological Process	GO:0009200	deoxyribonucleoside triphosphate metabolic process	IMP	J:122389
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	IBA	J:265628
Biological Process	GO:0009263	deoxyribonucleotide biosynthetic process	IDA	J:72397
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IMP	J:84841
Biological Process	GO:0000731	DNA synthesis involved in DNA repair	NAS	J:320121
Biological Process	GO:0001822	kidney development	IMP	J:84841
Biological Process	GO:0006264	mitochondrial DNA replication	ISO	J:164563
Biological Process	GO:0006264	mitochondrial DNA replication	IMP	J:122389
Biological Process	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:84841
Biological Process	GO:0070318	positive regulation of G0 to G1 transition	IDA	J:72397
Biological Process	GO:0070318	positive regulation of G0 to G1 transition	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0003014	renal system process	IMP	J:84841
Biological Process	GO:0006979	response to oxidative stress	IMP	J:84841
Biological Process	GO:0009185	ribonucleoside diphosphate metabolic process	ISO	J:164563