GO Annotations Graph

• Symbol: Wdr5
• Name: WD repeat domain 5
• ID: MGI:2155884

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:204007
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:175308
Molecular Function	GO:0005515	protein binding	IPI	J:184123
Molecular Function	GO:0005515	protein binding	IPI	J:145720
Molecular Function	GO:0005515	protein binding	IPI	J:145720
Molecular Function	GO:0005515	protein binding	IPI	J:193339
Molecular Function	GO:0005515	protein binding	IPI	J:189874
Molecular Function	GO:0005515	protein binding	IPI	J:163218
Molecular Function	GO:0005515	protein binding	IPI	J:145720
Molecular Function	GO:0005515	protein binding	IPI	J:145720
Cellular Component	GO:0140672	ATAC complex	IDA	J:314756
Cellular Component	GO:0140672	ATAC complex	ISO	J:164563
Cellular Component	GO:0000123	histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:164563
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:123598
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:73114
Cellular Component	GO:0072686	mitotic spindle	NAS	J:162081
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0044665	MLL1/2 complex	ISO	J:164563
Cellular Component	GO:0044666	MLL3/4 complex	ISO	J:164563
Cellular Component	GO:0044545	NSL complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619430
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619436
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619437
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619440
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621004
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5621012
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5693628
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810150
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810169
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810170
Cellular Component	GO:0005634	nucleus	IDA	J:209490
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:123598
Cellular Component	GO:0005634	nucleus	IDA	J:145720
Cellular Component	GO:0005634	nucleus	IDA	J:187077
Cellular Component	GO:0048188	Set1C/COMPASS complex	ISO	J:164563
Cellular Component	GO:0048188	Set1C/COMPASS complex	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006094	gluconeogenesis	IGI	J:204007
Biological Process	GO:0006094	gluconeogenesis	IGI	J:204007
Biological Process	GO:0043966	histone H3 acetylation	ISO	J:164563
Biological Process	GO:0044154	histone H3-K14 acetylation	ISO	J:164563
Biological Process	GO:0051568	histone H3-K4 methylation	IBA	J:265628
Biological Process	GO:0043984	histone H4-K16 acetylation	ISO	J:164563
Biological Process	GO:0043981	histone H4-K5 acetylation	ISO	J:164563
Biological Process	GO:0043982	histone H4-K8 acetylation	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0018022	peptidyl-lysine methylation	IMP	J:204007
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:313850
Biological Process	GO:0045722	positive regulation of gluconeogenesis	IGI	J:204007
Biological Process	GO:0045722	positive regulation of gluconeogenesis	IGI	J:204007
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:145720
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0051302	regulation of cell division	ISO	J:164563
Biological Process	GO:0051302	regulation of cell division	IDA	J:162081
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1900095	regulation of dosage compensation by inactivation of X chromosome	IDA	J:313850
Biological Process	GO:0045995	regulation of embryonic development	IDA	J:145720
Biological Process	GO:0031063	regulation of histone deacetylation	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0090043	regulation of tubulin deacetylation	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IDA	J:73114
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563