GO Annotations Graph

• Symbol: Acot8
• Name: acyl-CoA thioesterase 8
• ID: MGI:2158201

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047603	acetoacetyl-CoA hydrolase activity	IEA	J:72245
Molecular Function	GO:0003986	acetyl-CoA hydrolase activity	IEA	J:72245
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ISO	J:155856
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ISO	J:164563
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	IBA	J:265628
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	IDA	J:73690
Molecular Function	GO:0052689	carboxylic ester hydrolase activity	IEA	J:60000
Molecular Function	GO:0033882	choloyl-CoA hydrolase activity	ISO	J:155856
Molecular Function	GO:0044466	glutaryl-CoA hydrolase activity	IEA	J:72245
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0047994	hydroxymethylglutaryl-CoA hydrolase activity	IEA	J:72245
Molecular Function	GO:0052815	medium-chain acyl-CoA hydrolase activity	ISO	J:164563
Molecular Function	GO:0102991	myristoyl-CoA hydrolase activity	IEA	J:72245
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	ISO	J:164563
Molecular Function	GO:0004778	succinyl-CoA hydrolase activity	IEA	J:72245
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005782	peroxisomal matrix	ISO	J:164563
Cellular Component	GO:0005782	peroxisomal matrix	IBA	J:265628
Cellular Component	GO:0005777	peroxisome	IDA	J:116241
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Biological Process	GO:0006637	acyl-CoA metabolic process	ISO	J:164563
Biological Process	GO:0006637	acyl-CoA metabolic process	ISO	J:155856
Biological Process	GO:0006637	acyl-CoA metabolic process	IBA	J:265628
Biological Process	GO:0006637	acyl-CoA metabolic process	IDA	J:73690
Biological Process	GO:0043649	dicarboxylic acid catabolic process	ISO	J:164563
Biological Process	GO:0009062	fatty acid catabolic process	IBA	J:265628
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0045225	negative regulation of CD4 production	ISO	J:164563
Biological Process	GO:0016559	peroxisome fission	ISO	J:164563
Biological Process	GO:0007031	peroxisome organization	IEA	J:60000