GO Annotations Graph

• Symbol: Cln6
• Name: ceroid-lipofuscinosis, neuronal 6
• ID: MGI:2159324

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035727	lysophosphatidic acid binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISS	J:73921
Molecular Function	GO:0120146	sulfatide binding	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISS	J:73921
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISO	J:164563
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISS	J:73921
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Biological Process	GO:0008203	cholesterol metabolic process	ISS	J:73921
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0001573	ganglioside metabolic process	ISS	J:73921
Biological Process	GO:0001573	ganglioside metabolic process	ISO	J:164563
Biological Process	GO:0030203	glycosaminoglycan metabolic process	ISO	J:164563
Biological Process	GO:0030203	glycosaminoglycan metabolic process	ISS	J:73921
Biological Process	GO:0031987	locomotion involved in locomotory behavior	IMP	J:47292
Biological Process	GO:0007042	lysosomal lumen acidification	ISO	J:164563
Biological Process	GO:0007042	lysosomal lumen acidification	ISS	J:73921
Biological Process	GO:0007040	lysosome organization	IMP	J:229309
Biological Process	GO:0007040	lysosome organization	IMP	J:47292
Biological Process	GO:0009057	macromolecule catabolic process	IMP	J:112499
Biological Process	GO:0045862	positive regulation of proteolysis	ISO	J:164563
Biological Process	GO:0045862	positive regulation of proteolysis	ISS	J:73921
Biological Process	GO:0007601	visual perception	IMP	J:47292