Havcr2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Havcr2
hepatitis A virus cellular receptor 2
MGI:2159682

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:112653
Molecular Function	GO:0005515	protein binding	IPI	J:217479
Molecular Function	GO:0005515	protein binding	IPI	J:187594
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:224716
Cellular Component	GO:0005769	early endosome	IDA	J:187594
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0001772	immunological synapse	IDA	J:228106
Cellular Component	GO:0016592	mediator complex	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-5340404
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:228102
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:209885
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0002281	macrophage activation involved in immune response	IMP	J:187594
Biological Process	GO:0060135	maternal process involved in female pregnancy	IDA	J:222178
Biological Process	GO:0060135	maternal process involved in female pregnancy	ISO	J:164563
Biological Process	GO:0002519	natural killer cell tolerance induction	ISO	J:164563
Biological Process	GO:1900425	negative regulation of defense response to bacterium	IMP	J:187594
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0071656	negative regulation of granulocyte colony-stimulating factor production	ISO	J:164563
Biological Process	GO:0002838	negative regulation of immune response to tumor cell	IMP	J:187594
Biological Process	GO:2000521	negative regulation of immunological synapse formation	IMP	J:228106
Biological Process	GO:0045824	negative regulation of innate immune response	IMP	J:187594
Biological Process	GO:0032687	negative regulation of interferon-alpha production	ISO	J:164563
Biological Process	GO:0032703	negative regulation of interleukin-2 production	IMP	J:86226
Biological Process	GO:0032703	negative regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:0032712	negative regulation of interleukin-3 production	ISO	J:164563
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:187594
Biological Process	GO:0030886	negative regulation of myeloid dendritic cell activation	ISO	J:164563
Biological Process	GO:0032815	negative regulation of natural killer cell activation	IMP	J:228102
Biological Process	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IMP	J:187594
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	ISO	J:164563
Biological Process	GO:0042130	negative regulation of T cell proliferation	IMP	J:86226
Biological Process	GO:0002826	negative regulation of T-helper 1 type immune response	IMP	J:86226
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032480	negative regulation of type I interferon production	IMP	J:187594
Biological Process	GO:0032689	negative regulation of type II interferon production	IMP	J:86226
Biological Process	GO:0032689	negative regulation of type II interferon production	ISO	J:164563
Biological Process	GO:0032722	positive regulation of chemokine production	IMP	J:166066
Biological Process	GO:0001819	positive regulation of cytokine production	IMP	J:166066
Biological Process	GO:1900426	positive regulation of defense response to bacterium	IMP	J:166066
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:127314
Biological Process	GO:0045089	positive regulation of innate immune response	IMP	J:166066
Biological Process	GO:0032732	positive regulation of interleukin-1 production	IMP	J:166066
Biological Process	GO:0032753	positive regulation of interleukin-4 production	ISO	J:164563
Biological Process	GO:0043032	positive regulation of macrophage activation	IMP	J:166066
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IDA	J:127314
Biological Process	GO:0042102	positive regulation of T cell proliferation	IMP	J:209885
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:127314
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:209885
Biological Process	GO:0002652	regulation of tolerance induction dependent upon immune response	IMP	J:86226
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway	IMP	J:187594
Biological Process	GO:0034154	toll-like receptor 7 signaling pathway	IMP	J:187594
Biological Process	GO:0034162	toll-like receptor 9 signaling pathway	IMP	J:187594

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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