GO Annotations Graph

• Symbol: Slc26a6
• Name: solute carrier family 26, member 6
• ID: MGI:2159728

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	IDA	J:79463
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	IDA	J:75548
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005254	chloride channel activity	IEA	J:60000
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IDA	J:79463
Molecular Function	GO:0015108	chloride transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IDA	J:75548
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IMP	J:101422
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IDA	J:201564
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015108	chloride transmembrane transporter activity	IDA	J:75064
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:333163
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IMP	J:192779
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:201569
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:121543
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:75548
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	ISO	J:164563
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	ISO	J:164563
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IMP	J:263699
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IDA	J:333127
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IMP	J:333128
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	IMP	J:159253
Molecular Function	GO:0015562	efflux transmembrane transporter activity	IDA	J:79463
Molecular Function	GO:0015499	formate transmembrane transporter activity	IDA	J:79463
Molecular Function	GO:0015499	formate transmembrane transporter activity	IDA	J:201564
Molecular Function	GO:0015499	formate transmembrane transporter activity	IDA	J:75064
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	IMP	J:101422
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	IMP	J:201940
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	IDA	J:79463
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0030165	PDZ domain binding	IDA	J:101422
Molecular Function	GO:0005515	protein binding	IPI	J:101422
Molecular Function	GO:0005515	protein binding	IPI	J:220505
Molecular Function	GO:0005515	protein binding	IPI	J:185780
Molecular Function	GO:0008271	secondary active sulfate transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IMP	J:192779
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IDA	J:201569
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IMP	J:107558
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IDA	J:201564
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IDA	J:79463
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IMP	J:159253
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IMP	J:201940
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	ISO	J:164563
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IDA	J:75064
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IDA	J:333178
Molecular Function	GO:0015116	sulfate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015116	sulfate transmembrane transporter activity	IDA	J:79463
Molecular Function	GO:0015116	sulfate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015383	sulfate:bicarbonate antiporter activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:152870
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:75064
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:263699
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:101422
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:75548
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:121543
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0031526	brush border membrane	IDA	J:101422
Cellular Component	GO:0031526	brush border membrane	IDA	J:75548
Cellular Component	GO:0031526	brush border membrane	IDA	J:75064
Cellular Component	GO:0031526	brush border membrane	IDA	J:107558
Cellular Component	GO:0031526	brush border membrane	ISO	J:164563
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:185780
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:75548
Cellular Component	GO:0005886	plasma membrane	IDA	J:201564
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:333163
Cellular Component	GO:0005886	plasma membrane	IDA	J:75064
Cellular Component	GO:0097225	sperm midpiece	IDA	J:185780
Cellular Component	GO:0031982	vesicle	IDA	J:75548
Cellular Component	GO:0012506	vesicle membrane	IDA	J:101422
Cellular Component	GO:0012506	vesicle membrane	IDA	J:107558
Biological Process	GO:0038166	angiotensin-activated signaling pathway	ISO	J:164563
Biological Process	GO:0015701	bicarbonate transport	IMP	J:192779
Biological Process	GO:0015701	bicarbonate transport	IDA	J:79463
Biological Process	GO:0015701	bicarbonate transport	IDA	J:201569
Biological Process	GO:0015701	bicarbonate transport	ISO	J:164563
Biological Process	GO:0015701	bicarbonate transport	IMP	J:159253
Biological Process	GO:0015701	bicarbonate transport	ISO	J:164563
Biological Process	GO:0015701	bicarbonate transport	IMP	J:144738
Biological Process	GO:0015701	bicarbonate transport	IDA	J:75548
Biological Process	GO:0071320	cellular response to cAMP	IDA	J:192779
Biological Process	GO:0071332	cellular response to fructose stimulus	IDA	J:152870
Biological Process	GO:0071346	cellular response to type II interferon	ISO	J:164563
Biological Process	GO:0006821	chloride transport	IMP	J:159253
Biological Process	GO:0006821	chloride transport	IDA	J:79463
Biological Process	GO:0006821	chloride transport	IMP	J:107558
Biological Process	GO:0006821	chloride transport	IMP	J:101422
Biological Process	GO:0006821	chloride transport	IMP	J:192779
Biological Process	GO:0006821	chloride transport	ISO	J:164563
Biological Process	GO:0006821	chloride transport	IDA	J:201569
Biological Process	GO:0006821	chloride transport	IDA	J:201564
Biological Process	GO:0006821	chloride transport	ISO	J:164563
Biological Process	GO:0006821	chloride transport	IDA	J:75548
Biological Process	GO:0006821	chloride transport	IDA	J:75064
Biological Process	GO:0042045	epithelial fluid transport	IMP	J:152870
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:144738
Biological Process	GO:0015724	formate transport	IMP	J:192779
Biological Process	GO:0015724	formate transport	IDA	J:79463
Biological Process	GO:0015724	formate transport	IDA	J:201569
Biological Process	GO:0015724	formate transport	IDA	J:201564
Biological Process	GO:0015724	formate transport	IDA	J:75064
Biological Process	GO:0050892	intestinal absorption	IMP	J:201940
Biological Process	GO:0051454	intracellular pH elevation	IMP	J:185780
Biological Process	GO:0015797	mannitol transmembrane transport	IMP	J:201940
Biological Process	GO:0006820	monoatomic anion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0019532	oxalate transport	IMP	J:107558
Biological Process	GO:0019532	oxalate transport	IDA	J:201569
Biological Process	GO:0019532	oxalate transport	IDA	J:79463
Biological Process	GO:0019532	oxalate transport	IMP	J:201940
Biological Process	GO:0019532	oxalate transport	ISO	J:164563
Biological Process	GO:0019532	oxalate transport	IMP	J:101422
Biological Process	GO:0046724	oxalic acid secretion	IMP	J:201940
Biological Process	GO:2001150	positive regulation of dipeptide transmembrane transport	IMP	J:159253
Biological Process	GO:0070528	protein kinase C signaling	ISO	J:164563
Biological Process	GO:0070528	protein kinase C signaling	IDA	J:201564
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:164563
Biological Process	GO:0051453	regulation of intracellular pH	IMP	J:159253
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:164563
Biological Process	GO:0048240	sperm capacitation	IMP	J:185780
Biological Process	GO:0008272	sulfate transport	IDA	J:201569
Biological Process	GO:0008272	sulfate transport	ISO	J:164563
Biological Process	GO:0008272	sulfate transport	IMP	J:107558
Biological Process	GO:0008272	sulfate transport	IDA	J:79463
Biological Process	GO:0030321	transepithelial chloride transport	ISO	J:164563
Biological Process	GO:0030321	transepithelial chloride transport	IMP	J:192779
Biological Process	GO:0030321	transepithelial chloride transport	IDA	J:75064
Biological Process	GO:0070633	transepithelial transport	IMP	J:107558
Biological Process	GO:0070633	transepithelial transport	IMP	J:159253
Biological Process	GO:0070633	transepithelial transport	IMP	J:101422
Biological Process	GO:0070633	transepithelial transport	IMP	J:201940
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247