GO Annotations Graph

• Symbol: Cyp26b1
• Name: cytochrome P450, family 26, subfamily b, polypeptide 1
• ID: MGI:2176159

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IBA	J:265628
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	J:72247
Molecular Function	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	ISO	J:164563
Molecular Function	GO:0008401	retinoic acid 4-hydroxylase activity	ISO	J:155856
Molecular Function	GO:0008401	retinoic acid 4-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0001972	retinoic acid binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0060349	bone morphogenesis	ISO	J:164563
Biological Process	GO:0001709	cell fate determination	IMP	J:108333
Biological Process	GO:0071300	cellular response to retinoic acid	IEP	J:139633
Biological Process	GO:0070268	cornification	IMP	J:192725
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:89029
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:192725
Biological Process	GO:0001768	establishment of T cell polarity	IMP	J:205957
Biological Process	GO:0006954	inflammatory response	IMP	J:205957
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:108333
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	IMP	J:192725
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:139633
Biological Process	GO:2001037	positive regulation of tongue muscle cell differentiation	IMP	J:139633
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:89029
Biological Process	GO:0048385	regulation of retinoic acid receptor signaling pathway	IMP	J:205957
Biological Process	GO:0045580	regulation of T cell differentiation	IMP	J:205957
Biological Process	GO:0034653	retinoic acid catabolic process	ISO	J:155856
Biological Process	GO:0034653	retinoic acid catabolic process	ISO	J:164563
Biological Process	GO:0034653	retinoic acid catabolic process	IC	J:192725
Biological Process	GO:0042573	retinoic acid metabolic process	ISO	J:164563
Biological Process	GO:0042573	retinoic acid metabolic process	IC	J:89029
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IMP	J:139633
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IDA	J:106963
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IMP	J:192725
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	IDA	J:89029
Biological Process	GO:0007283	spermatogenesis	IMP	J:108333
Biological Process	GO:0016125	sterol metabolic process	IBA	J:265628
Biological Process	GO:0043587	tongue morphogenesis	IMP	J:139633
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:164563