GO Annotations Graph

• Symbol: Ucn2
• Name: urocortin 2
• ID: MGI:2176375

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051431	corticotropin-releasing hormone receptor 2 binding	ISO	J:155856
Molecular Function	GO:0051429	corticotropin-releasing hormone receptor binding	ISO	J:164563
Molecular Function	GO:0051429	corticotropin-releasing hormone receptor binding	ISS	J:114061
Molecular Function	GO:0051429	corticotropin-releasing hormone receptor binding	IBA	J:265628
Molecular Function	GO:0001664	G protein-coupled receptor binding	IDA	J:95540
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0005179	hormone activity	IEA	J:72247
Molecular Function	GO:0042562	hormone binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:95540
Molecular Function	GO:0005515	protein binding	IPI	J:70028
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	ISO	J:155856
Biological Process	GO:0031669	cellular response to nutrient levels	IBA	J:265628
Biological Process	GO:0007586	digestion	IEA	J:72247
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0009755	hormone-mediated signaling pathway	ISS	J:114061
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0046882	negative regulation of follicle-stimulating hormone secretion	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0033685	negative regulation of luteinizing hormone secretion	ISO	J:155856