GO Annotations Graph

• Symbol: Bco2
• Name: beta-carotene oxygenase 2
• ID: MGI:2177469

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0102076	beta,beta-carotene-9',10'-cleaving oxygenase activity	IDA	J:74948
Molecular Function	GO:0102076	beta,beta-carotene-9',10'-cleaving oxygenase activity	IDA	J:170742
Molecular Function	GO:0003834	beta-carotene 15,15'-dioxygenase activity	IBA	J:265628
Molecular Function	GO:0010436	carotenoid dioxygenase activity	IBA	J:265628
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IDA	J:74948
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ISO	J:164563
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IDA	J:170742
Cellular Component	GO:0005739	mitochondrion	IDA	J:170742
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Biological Process	GO:0016121	carotene catabolic process	IDA	J:170742
Biological Process	GO:0016121	carotene catabolic process	ISO	J:164563
Biological Process	GO:0016121	carotene catabolic process	IDA	J:74948
Biological Process	GO:0016121	carotene catabolic process	IBA	J:265628
Biological Process	GO:0016119	carotene metabolic process	IDA	J:74948
Biological Process	GO:0016119	carotene metabolic process	ISO	J:164563
Biological Process	GO:0016116	carotenoid metabolic process	IMP	J:170742
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	IMP	J:170742
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	IMP	J:170742
Biological Process	GO:0042574	retinal metabolic process	NAS	J:74948
Biological Process	GO:0042574	retinal metabolic process	IBA	J:265628
Biological Process	GO:0042574	retinal metabolic process	IGI	J:221145
Biological Process	GO:0042573	retinoic acid metabolic process	NAS	J:74948
Biological Process	GO:0016124	xanthophyll catabolic process	IDA	J:170742
Biological Process	GO:0016122	xanthophyll metabolic process	IMP	J:221145