Nlgn1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nlgn1
neuroligin 1
MGI:2179435

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042043	neurexin family protein binding	ISO	J:155856
Molecular Function	GO:0042043	neurexin family protein binding	IPI	J:175147
Molecular Function	GO:0042043	neurexin family protein binding	IMP	J:116404
Molecular Function	GO:0042043	neurexin family protein binding	IPI	J:84070
Molecular Function	GO:0042043	neurexin family protein binding	IBA	J:265628
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:245291
Molecular Function	GO:0005515	protein binding	IPI	J:200384
Molecular Function	GO:0005515	protein binding	IPI	J:243475
Molecular Function	GO:0005515	protein binding	IPI	J:298861
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:243525
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:201692
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	IC	J:138036
Cellular Component	GO:0060076	excitatory synapse	IC	J:116404
Cellular Component	GO:0060076	excitatory synapse	NAS	J:138036
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:161514
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0032433	filopodium tip	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	NAS	J:319984
Cellular Component	GO:0098978	glutamatergic synapse	NAS	J:319984
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:175189
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:175189
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:175189
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0060077	inhibitory synapse	NAS	J:138036
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0031594	neuromuscular junction	NAS	J:320287
Cellular Component	GO:0098984	neuron to neuron synapse	NAS	J:319989
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IMP	J:116404
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0098635	protein complex involved in cell-cell adhesion	EXP	J:245291
Cellular Component	GO:0098635	protein complex involved in cell-cell adhesion	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	IDA	J:84070
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:78720
Cellular Component	GO:0045202	synapse	IDA	J:96464
Biological Process	GO:0097113	AMPA glutamate receptor clustering	ISO	J:155856
Biological Process	GO:0097113	AMPA glutamate receptor clustering	IMP	J:184102
Biological Process	GO:0097113	AMPA glutamate receptor clustering	IDA	J:84070
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	NAS	J:245291
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	ISO	J:155856
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IDA	J:84070
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0090125	cell-cell adhesion involved in synapse maturation	NAS	J:319989
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0048789	cytoskeletal matrix organization at active zone	ISO	J:155856
Biological Process	GO:0048789	cytoskeletal matrix organization at active zone	IMP	J:152008
Biological Process	GO:0045184	establishment of protein localization	IMP	J:84070
Biological Process	GO:1904861	excitatory synapse assembly	IDA	J:232984
Biological Process	GO:1904861	excitatory synapse assembly	IMP	J:243525
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IDA	J:84070
Biological Process	GO:0060291	long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:0099558	maintenance of synapse structure	NAS	J:319951
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IGI	J:113647
Biological Process	GO:0061002	negative regulation of dendritic spine morphogenesis	IMP	J:197488
Biological Process	GO:0061002	negative regulation of dendritic spine morphogenesis	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IDA	J:116404
Biological Process	GO:0007399	nervous system development	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IMP	J:247060
Biological Process	GO:0097115	neurexin clustering involved in presynaptic membrane assembly	IDA	J:84070
Biological Process	GO:0007158	neuron cell-cell adhesion	ISO	J:155856
Biological Process	GO:0007158	neuron cell-cell adhesion	IDA	J:84070
Biological Process	GO:0007158	neuron cell-cell adhesion	NAS	J:319989
Biological Process	GO:0007158	neuron cell-cell adhesion	IBA	J:265628
Biological Process	GO:0140058	neuron projection arborization	ISO	J:155856
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0048812	neuron projection morphogenesis	NAS	J:319951
Biological Process	GO:0097114	NMDA glutamate receptor clustering	ISO	J:155856
Biological Process	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	IMP	J:197398
Biological Process	GO:0060999	positive regulation of dendritic spine development	IMP	J:197488
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:164563
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	ISO	J:164563
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:197488
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IDA	J:138036
Biological Process	GO:0051491	positive regulation of filopodium assembly	ISO	J:155856
Biological Process	GO:1902533	positive regulation of intracellular signal transduction	ISO	J:155856
Biological Process	GO:1900075	positive regulation of neuromuscular synaptic transmission	NAS	J:320287
Biological Process	GO:0010976	positive regulation of neuron projection development	NAS	J:319951
Biological Process	GO:1905520	positive regulation of presynaptic active zone assembly	ISO	J:155856
Biological Process	GO:1902474	positive regulation of protein localization to synapse	ISO	J:155856
Biological Process	GO:1900029	positive regulation of ruffle assembly	ISO	J:155856
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:155856
Biological Process	GO:0051965	positive regulation of synapse assembly	IDA	J:171950
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:211830
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	ISO	J:155856
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	NAS	J:319984
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	NAS	J:319984
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	IDA	J:175189
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	IMP	J:152008
Biological Process	GO:2000302	positive regulation of synaptic vesicle exocytosis	IMP	J:152008
Biological Process	GO:2000302	positive regulation of synaptic vesicle exocytosis	ISO	J:155856
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IDA	J:180545
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IDA	J:84070
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	ISO	J:155856
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IDA	J:175189
Biological Process	GO:0097104	postsynaptic membrane assembly	IDA	J:175189
Biological Process	GO:0097104	postsynaptic membrane assembly	IDA	J:84070
Biological Process	GO:0097104	postsynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:175189
Biological Process	GO:0097105	presynaptic membrane assembly	ISO	J:155856
Biological Process	GO:0097105	presynaptic membrane assembly	IDA	J:116404
Biological Process	GO:0097105	presynaptic membrane assembly	IDA	J:175189
Biological Process	GO:0097105	presynaptic membrane assembly	IDA	J:84070
Biological Process	GO:0097105	presynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0035418	protein localization to synapse	IDA	J:175189
Biological Process	GO:0035418	protein localization to synapse	IDA	J:232984
Biological Process	GO:0006605	protein targeting	ISO	J:155856
Biological Process	GO:0097120	receptor localization to synapse	IDA	J:84070
Biological Process	GO:2000311	regulation of AMPA receptor activity	ISO	J:155856
Biological Process	GO:0045664	regulation of neuron differentiation	IDA	J:116404
Biological Process	GO:2000310	regulation of NMDA receptor activity	IDA	J:138036
Biological Process	GO:2000310	regulation of NMDA receptor activity	IMP	J:197488
Biological Process	GO:2000310	regulation of NMDA receptor activity	ISO	J:164563
Biological Process	GO:2000310	regulation of NMDA receptor activity	ISO	J:155856
Biological Process	GO:0099174	regulation of presynapse organization	ISO	J:155856
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IGI	J:113647
Biological Process	GO:0098942	retrograde trans-synaptic signaling by trans-synaptic protein complex	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0007416	synapse assembly	IDA	J:116404
Biological Process	GO:0007416	synapse assembly	NAS	J:319989
Biological Process	GO:0007416	synapse assembly	ISO	J:155856
Biological Process	GO:0007416	synapse assembly	IDA	J:171950
Biological Process	GO:0007416	synapse assembly	IDA	J:171950
Biological Process	GO:0060074	synapse maturation	NAS	J:319989
Biological Process	GO:0050808	synapse organization	IGI	J:176974
Biological Process	GO:0050808	synapse organization	IGI	J:176974
Biological Process	GO:0050808	synapse organization	IGI	J:176974
Biological Process	GO:0050808	synapse organization	ISO	J:96464
Biological Process	GO:0099560	synaptic membrane adhesion	IMP	J:230665
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:84070
Biological Process	GO:0099560	synaptic membrane adhesion	IMP	J:84070
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:84070
Biological Process	GO:0097091	synaptic vesicle clustering	IDA	J:116404
Biological Process	GO:0097091	synaptic vesicle clustering	ISO	J:155856
Biological Process	GO:0097091	synaptic vesicle clustering	IDA	J:84070
Biological Process	GO:0048488	synaptic vesicle endocytosis	IBA	J:265628
Biological Process	GO:0016080	synaptic vesicle targeting	IMP	J:116404
Biological Process	GO:0048489	synaptic vesicle transport	ISO	J:155856
Biological Process	GO:0072553	terminal button organization	IMP	J:152008
Biological Process	GO:0072553	terminal button organization	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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