GO Annotations Graph

• Symbol: Casc3
• Name: exon junction complex subunit
• ID: MGI:2179723

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:77721
Molecular Function	GO:0003729	mRNA binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:87058
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:87058
Cellular Component	GO:0035145	exon-exon junction complex	ISO	J:164563
Cellular Component	GO:0035145	exon-exon junction complex	IBA	J:265628
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:87058
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:87058
Cellular Component	GO:0005681	spliceosomal complex	IEA	J:60000
Cellular Component	GO:0071006	U2-type catalytic step 1 spliceosome	ISO	J:164563
Biological Process	GO:0008298	intracellular mRNA localization	IDA	J:87058
Biological Process	GO:0006406	mRNA export from nucleus	NAS	J:320148
Biological Process	GO:0006397	mRNA processing	IEA	J:72247
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0000398	mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA	J:60000
Biological Process	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	ISO	J:164563
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0008380	RNA splicing	IEA	J:60000