GO Annotations Graph

• Symbol: Rac3
• Name: Rac family small GTPase 3
• ID: MGI:2180784

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:112529
Molecular Function	GO:0005515	protein binding	IPI	J:112529
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Cellular Component	GO:0005938	cell cortex	IBA	J:265628
Cellular Component	GO:0071944	cell periphery	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0012505	endomembrane system	ISO	J:164563
Cellular Component	GO:0031941	filamentous actin	ISO	J:112529
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:112529
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:112529
Cellular Component	GO:0043025	neuronal cell body	ISO	J:112529
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0030031	cell projection assembly	ISO	J:164563
Biological Process	GO:0021894	cerebral cortex GABAergic interneuron development	IGI	J:210135
Biological Process	GO:0030865	cortical cytoskeleton organization	IBA	J:265628
Biological Process	GO:0043652	engulfment of apoptotic cell	IBA	J:265628
Biological Process	GO:0007163	establishment or maintenance of cell polarity	IBA	J:265628
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IGI	J:210135
Biological Process	GO:0008045	motor neuron axon guidance	IBA	J:265628
Biological Process	GO:0050905	neuromuscular process	IMP	J:99180
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:99180
Biological Process	GO:0031175	neuron projection development	IDA	J:112529
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0016601	Rac protein signal transduction	IBA	J:265628
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0022604	regulation of cell morphogenesis	IGI	J:210135
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0014041	regulation of neuron maturation	IGI	J:210135
Biological Process	GO:0007264	small GTPase mediated signal transduction	IEA	J:72247
Biological Process	GO:0051932	synaptic transmission, GABAergic	IGI	J:210135
Biological Process	GO:0016055	Wnt signaling pathway	ISO	J:164563