GO Annotations Graph

• Symbol: Oas3
• Name: 2'-5' oligoadenylate synthetase 3
• ID: MGI:2180850

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	ISO	J:164563
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	IBA	J:265628
Molecular Function	GO:0001730	2'-5'-oligoadenylate synthetase activity	IDA	J:175745
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0003725	double-stranded RNA binding	IBA	J:265628
Molecular Function	GO:0003725	double-stranded RNA binding	IDA	J:175745
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016779	nucleotidyltransferase activity	IEA	J:60000
Molecular Function	GO:0016779	nucleotidyltransferase activity	IEA	J:72247
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0042742	defense response to bacterium	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0039530	MDA-5 signaling pathway	ISO	J:164563
Biological Process	GO:0071650	negative regulation of chemokine (C-C motif) ligand 5 production	ISO	J:164563
Biological Process	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production	ISO	J:164563
Biological Process	GO:0035395	negative regulation of chemokine (C-X-C motif) ligand 9 production	ISO	J:164563
Biological Process	GO:0071659	negative regulation of IP-10 production	ISO	J:164563
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	IBA	J:265628
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0060700	regulation of ribonuclease activity	ISO	J:164563
Biological Process	GO:0060700	regulation of ribonuclease activity	IBA	J:265628
Biological Process	GO:0009615	response to virus	ISO	J:164563
Biological Process	GO:0039529	RIG-I signaling pathway	ISO	J:164563