GO Annotations Graph

• Symbol: Hps6
• Name: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
• ID: MGI:2181763

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:236210
Molecular Function	GO:0005515	protein binding	IPI	J:81444
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Cellular Component	GO:0031084	BLOC-2 complex	ISO	J:164563
Cellular Component	GO:0031084	BLOC-2 complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005769	early endosome	NAS	J:320067
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0007596	blood coagulation	IMP	J:7327
Biological Process	GO:0046907	intracellular transport	NAS	J:236210
Biological Process	GO:0032418	lysosome localization	ISO	J:164563
Biological Process	GO:0032418	lysosome localization	IMP	J:236210
Biological Process	GO:0032418	lysosome localization	IBA	J:265628
Biological Process	GO:1903232	melanosome assembly	NAS	J:320067
Biological Process	GO:0006996	organelle organization	IBA	J:265628
Biological Process	GO:0006996	organelle organization	IMP	J:81444
Biological Process	GO:0043473	pigmentation	IMP	J:94897
Biological Process	GO:0043473	pigmentation	IMP	J:29467
Biological Process	GO:0043473	pigmentation	IMP	J:12970
Biological Process	GO:0043473	pigmentation	IMP	J:29467
Biological Process	GO:0060155	platelet dense granule organization	NAS	J:320067
Biological Process	GO:0072657	protein localization to membrane	ISO	J:164563
Biological Process	GO:0072657	protein localization to membrane	IBA	J:265628