GO Annotations Graph

• Symbol: Usp7
• Name: ubiquitin specific peptidase 7
• ID: MGI:2182061

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IDA	J:188893
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:155856
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IMP	J:238487
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IBA	J:265628
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:227354
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IMP	J:188893
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0101005	deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:238487
Molecular Function	GO:0005515	protein binding	IPI	J:141030
Molecular Function	GO:0005515	protein binding	IPI	J:188893
Molecular Function	GO:0005515	protein binding	IPI	J:222892
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:77464
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:77464
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0001741	XY body	IDA	J:222892
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	ISO	J:227354
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0044027	negative regulation of gene expression via CpG island methylation	ISO	J:164563
Biological Process	GO:0045721	negative regulation of gluconeogenesis	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1901537	positive regulation of DNA demethylation	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	IDA	J:188893
Biological Process	GO:0016579	protein deubiquitination	ISO	J:155856
Biological Process	GO:0016579	protein deubiquitination	IBA	J:265628
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0042752	regulation of circadian rhythm	ISO	J:164563
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:283196
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	ISO	J:155856
Biological Process	GO:0031647	regulation of protein stability	IMP	J:283196
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0031647	regulation of protein stability	IBA	J:265628
Biological Process	GO:1905279	regulation of retrograde transport, endosome to Golgi	ISO	J:164563
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	J:72247