GO Annotations Graph

• Symbol: Ash1l
• Name: ASH1 like histone lysine methyltransferase
• ID: MGI:2183158

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0140955	histone H3K36 trimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IDA	J:208213
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IDA	J:269562
Molecular Function	GO:0140948	histone H3K9 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0046697	decidualization	IMP	J:227516
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:227516
Biological Process	GO:0097676	histone H3-K36 dimethylation	ISO	J:164563
Biological Process	GO:0097676	histone H3-K36 dimethylation	IBA	J:265628
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IMP	J:208213
Biological Process	GO:0006954	inflammatory response	IGI	J:208213
Biological Process	GO:0006954	inflammatory response	IGI	J:208213
Biological Process	GO:0032635	interleukin-6 production	IGI	J:208213
Biological Process	GO:0032635	interleukin-6 production	IGI	J:208213
Biological Process	GO:0010934	macrophage cytokine production	IGI	J:208213
Biological Process	GO:0010934	macrophage cytokine production	IGI	J:208213
Biological Process	GO:0000165	MAPK cascade	IMP	J:208213
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0002674	negative regulation of acute inflammatory response	IMP	J:208213
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:208213
Biological Process	GO:0050728	negative regulation of inflammatory response	IGI	J:208213
Biological Process	GO:0050728	negative regulation of inflammatory response	IGI	J:208213
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:208213
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:208213
Biological Process	GO:0009791	post-embryonic development	IMP	J:227516
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0010468	regulation of gene expression	IMP	J:227516
Biological Process	GO:0048733	sebaceous gland development	IMP	J:227516
Biological Process	GO:0007338	single fertilization	IMP	J:227516
Biological Process	GO:0001501	skeletal system development	IMP	J:227516
Biological Process	GO:1903699	tarsal gland development	IMP	J:227516
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:208213
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:208213
Biological Process	GO:1903709	uterine gland development	IMP	J:227516
Biological Process	GO:0061038	uterus morphogenesis	IMP	J:227516