GO Annotations Graph

• Symbol: Agap3
• Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
• ID: MGI:2183446

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	IDA	J:105718
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	IDA	J:105718
Cellular Component	GO:0071944	cell periphery	IDA	J:105718
Cellular Component	GO:0005737	cytoplasm	IDA	J:105718
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:105718
Cellular Component	GO:0016605	PML body	ISO	J:105718
Biological Process	GO:0090630	activation of GTPase activity	IBA	J:265628
Biological Process	GO:0034614	cellular response to reactive oxygen species	ISO	J:105718
Biological Process	GO:0034614	cellular response to reactive oxygen species	IDA	J:105718
Biological Process	GO:0034644	cellular response to UV	ISO	J:105718
Biological Process	GO:0030578	PML body organization	ISO	J:105718
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	J:105718
Biological Process	GO:0006606	protein import into nucleus	IMP	J:105718