GO Annotations Graph

• Symbol: Fgd4
• Name: FYVE, RhoGEF and PH domain containing 4
• ID: MGI:2183747

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:78214
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IEA	J:60000
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030175	filopodium	IDA	J:76629
Cellular Component	GO:0030027	lamellipodium	IDA	J:76629
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0046847	filopodium assembly	IBA	J:265628
Biological Process	GO:0030032	lamellipodium assembly	IDA	J:76629
Biological Process	GO:0030035	microspike assembly	IDA	J:76629
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:155856
Biological Process	GO:0043507	positive regulation of JUN kinase activity	ISO	J:78214
Biological Process	GO:0008360	regulation of cell shape	ISO	J:155856