GO Annotations Graph

• Symbol: Alkbh1
• Name: alkB homolog 1, histone H2A dioxygenase
• ID: MGI:2384034

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	ISO	J:164563
Molecular Function	GO:0042056	chemoattractant activity	IDA	J:114625
Molecular Function	GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	ISO	J:164563
Molecular Function	GO:0008198	ferrous iron binding	ISO	J:164563
Molecular Function	GO:0008198	ferrous iron binding	IBA	J:265628
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	ISO	J:164563
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ISO	J:164563
Molecular Function	GO:0035516	oxidative DNA demethylase activity	IDA	J:276409
Molecular Function	GO:0035516	oxidative DNA demethylase activity	IBA	J:265628
Molecular Function	GO:0035515	oxidative RNA demethylase activity	ISO	J:164563
Molecular Function	GO:0035515	oxidative RNA demethylase activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:131022
Molecular Function	GO:0000049	tRNA binding	ISO	J:164563
Molecular Function	GO:1990984	tRNA demethylase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0000791	euchromatin	IDA	J:131022
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IMP	J:131022
Biological Process	GO:0048589	developmental growth	IMP	J:131022
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ISO	J:164563
Biological Process	GO:0080111	DNA demethylation	ISO	J:164563
Biological Process	GO:0080111	DNA demethylation	IDA	J:276409
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0001701	in utero embryonic development	IMP	J:131022
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:114625
Biological Process	GO:0001764	neuron migration	IDA	J:114625
Biological Process	GO:0031175	neuron projection development	IDA	J:114625
Biological Process	GO:0070989	oxidative demethylation	ISO	J:164563
Biological Process	GO:0035513	oxidative RNA demethylation	ISO	J:164563
Biological Process	GO:0035513	oxidative RNA demethylation	IBA	J:265628
Biological Process	GO:0035552	oxidative single-stranded DNA demethylation	IBA	J:265628
Biological Process	GO:0001890	placenta development	IMP	J:131022
Biological Process	GO:0010468	regulation of gene expression	IMP	J:131022
Biological Process	GO:0070129	regulation of mitochondrial translation	ISO	J:164563
Biological Process	GO:0006448	regulation of translational elongation	ISO	J:164563
Biological Process	GO:0006446	regulation of translational initiation	ISO	J:164563
Biological Process	GO:0042245	RNA repair	ISO	J:164563
Biological Process	GO:1990983	tRNA demethylation	IMP	J:276420
Biological Process	GO:1990983	tRNA demethylation	ISO	J:164563
Biological Process	GO:0002101	tRNA wobble cytosine modification	ISO	J:164563