GO Annotations Graph

• Symbol: Nphp4
• Name: nephronophthisis 4 (juvenile) homolog (human)
• ID: MGI:2384210

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:173396
Molecular Function	GO:0005515	protein binding	IPI	J:173396
Molecular Function	GO:0005515	protein binding	IPI	J:264617
Molecular Function	GO:0005515	protein binding	IPI	J:212147
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005814	centriole	IDA	J:255486
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0036064	ciliary basal body	ISO	J:155856
Cellular Component	GO:0036064	ciliary basal body	IBA	J:265628
Cellular Component	GO:0097546	ciliary base	IBA	J:265628
Cellular Component	GO:0097546	ciliary base	IDA	J:212148
Cellular Component	GO:0035869	ciliary transition zone	IBA	J:265628
Cellular Component	GO:0035869	ciliary transition zone	IDA	J:212148
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:173396
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0097730	non-motile cilium	IBA	J:265628
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0032391	photoreceptor connecting cilium	IDA	J:167232
Cellular Component	GO:0120206	photoreceptor distal connecting cilium	IDA	J:264617
Cellular Component	GO:0097470	ribbon synapse	IDA	J:167232
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:167232
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:167232
Biological Process	GO:0035845	photoreceptor cell outer segment organization	IMP	J:167232
Biological Process	GO:1903348	positive regulation of bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:1904491	protein localization to ciliary transition zone	IBA	J:265628
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:166679