GO Annotations Graph

• Symbol: Aars1
• Name: alanyl-tRNA synthetase 1
• ID: MGI:2384560

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004813	alanine-tRNA ligase activity	ISO	J:155856
Molecular Function	GO:0004813	alanine-tRNA ligase activity	IDA	J:242411
Molecular Function	GO:0004813	alanine-tRNA ligase activity	ISO	J:164563
Molecular Function	GO:0004813	alanine-tRNA ligase activity	IBA	J:265628
Molecular Function	GO:0016597	amino acid binding	ISO	J:155856
Molecular Function	GO:0016597	amino acid binding	IBA	J:265628
Molecular Function	GO:0002161	aminoacyl-tRNA editing activity	ISO	J:164563
Molecular Function	GO:0002161	aminoacyl-tRNA editing activity	IDA	J:161090
Molecular Function	GO:0002161	aminoacyl-tRNA editing activity	IBA	J:265628
Molecular Function	GO:0004812	aminoacyl-tRNA ligase activity	IEA	J:60000
Molecular Function	GO:0004812	aminoacyl-tRNA ligase activity	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0005524	ATP binding	IBA	J:265628
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:262421
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0002196	Ser-tRNA(Ala) hydrolase activity	IDA	J:216802
Molecular Function	GO:0002196	Ser-tRNA(Ala) hydrolase activity	IMP	J:110647
Molecular Function	GO:0002196	Ser-tRNA(Ala) hydrolase activity	IMP	J:262421
Molecular Function	GO:0002196	Ser-tRNA(Ala) hydrolase activity	IMP	J:216802
Molecular Function	GO:0045182	translation regulator activity	IMP	J:216802
Molecular Function	GO:0000049	tRNA binding	ISO	J:155856
Molecular Function	GO:0000049	tRNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Biological Process	GO:0006419	alanyl-tRNA aminoacylation	ISO	J:155856
Biological Process	GO:0006419	alanyl-tRNA aminoacylation	IDA	J:242411
Biological Process	GO:0006419	alanyl-tRNA aminoacylation	ISO	J:164563
Biological Process	GO:0006419	alanyl-tRNA aminoacylation	IBA	J:265628
Biological Process	GO:0006419	alanyl-tRNA aminoacylation	IMP	J:110647
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	IMP	J:110647
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:110647
Biological Process	GO:0050905	neuromuscular process	IMP	J:110647
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:110647
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:110647
Biological Process	GO:0140018	regulation of cytoplasmic translational fidelity	IMP	J:216802
Biological Process	GO:0006412	translation	IEA	J:60000
Biological Process	GO:0043039	tRNA aminoacylation	IEA	J:72247
Biological Process	GO:0006400	tRNA modification	IDA	J:216802
Biological Process	GO:0006400	tRNA modification	IMP	J:262421
Biological Process	GO:0006400	tRNA modification	IBA	J:265628
Biological Process	GO:0006400	tRNA modification	IMP	J:110647