GO Annotations Graph

• Symbol: Eif4g1
• Name: eukaryotic translation initiation factor 4, gamma 1
• ID: MGI:2384784

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0008190	eukaryotic initiation factor 4E binding	ISO	J:155856
Molecular Function	GO:0008190	eukaryotic initiation factor 4E binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:109360
Molecular Function	GO:0005515	protein binding	IPI	J:145850
Molecular Function	GO:0005515	protein binding	IPI	J:194400
Molecular Function	GO:0005515	protein binding	IPI	J:141655
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0008135	translation factor activity, RNA binding	ISO	J:164563
Molecular Function	GO:0003743	translation initiation factor activity	ISO	J:164563
Molecular Function	GO:0003743	translation initiation factor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:82058
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016281	eukaryotic translation initiation factor 4F complex	ISO	J:164563
Cellular Component	GO:0016281	eukaryotic translation initiation factor 4F complex	ISO	J:155856
Cellular Component	GO:0016281	eukaryotic translation initiation factor 4F complex	NAS	J:320123
Cellular Component	GO:0016281	eukaryotic translation initiation factor 4F complex	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005844	polysome	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Biological Process	GO:0001662	behavioral fear response	IGI	J:212538
Biological Process	GO:0001662	behavioral fear response	IGI	J:212538
Biological Process	GO:0031669	cellular response to nutrient levels	ISO	J:164563
Biological Process	GO:0097009	energy homeostasis	ISO	J:164563
Biological Process	GO:0009059	macromolecule biosynthetic process	ISO	J:164563
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	ISO	J:164563
Biological Process	GO:0010507	negative regulation of autophagy	ISO	J:164563
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0030182	neuron differentiation	IMP	J:217461
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:1905537	positive regulation of eukaryotic translation initiation factor 4F complex assembly	ISO	J:164563
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:1905612	positive regulation of mRNA cap binding	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:217461
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:1905696	regulation of polysome binding	ISO	J:164563
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:164563
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0006446	regulation of translational initiation	ISO	J:164563
Biological Process	GO:0006412	translation	ISO	J:164563
Biological Process	GO:0006413	translational initiation	ISO	J:164563
Biological Process	GO:0006413	translational initiation	NAS	J:320123