GO Annotations Graph

• Symbol: Prdm9
• Name: PR domain containing 9
• ID: MGI:2384854

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IMP	J:233373
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0140955	histone H3K36 trimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:290204
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	EXP	J:102875
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:233373
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IDA	J:277873
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:180577
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IDA	J:102875
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:102875
Molecular Function	GO:0140949	histone H3K9 trimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0140944	histone H4K20 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0140941	histone H4K20me methyltransferase activity	IEA	J:72245
Molecular Function	GO:0042054	histone methyltransferase activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:277855
Molecular Function	GO:0005515	protein binding	IPI	J:267768
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:277873
Molecular Function	GO:0010844	recombination hotspot binding	ISO	J:164563
Molecular Function	GO:0010844	recombination hotspot binding	IBA	J:265628
Molecular Function	GO:0010844	recombination hotspot binding	IDA	J:180577
Molecular Function	GO:0010844	recombination hotspot binding	IMP	J:213187
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:180577
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0000785	chromatin	IDA	J:255344
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-1214198
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912383
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-1214205
Cellular Component	GO:0005654	nucleoplasm	IC	J:102875
Cellular Component	GO:0005634	nucleus	IDA	J:250814
Cellular Component	GO:0005634	nucleus	IDA	J:277855
Cellular Component	GO:0005634	nucleus	IDA	J:255344
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	IMP	J:250814
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	IMP	J:255344
Biological Process	GO:0007292	female gamete generation	IMP	J:255344
Biological Process	GO:0016571	histone methylation	IEA	J:72247
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:255344
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:250814
Biological Process	GO:0048232	male gamete generation	IMP	J:255344
Biological Process	GO:0007127	meiosis I	IMP	J:102875
Biological Process	GO:0007127	meiosis I	IMP	J:102875
Biological Process	GO:0007127	meiosis I	IMP	J:102875
Biological Process	GO:0007127	meiosis I	IMP	J:102875
Biological Process	GO:0051321	meiotic cell cycle	IEA	J:60000
Biological Process	GO:0006311	meiotic gene conversion	ISO	J:73065
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:277855
Biological Process	GO:1905516	positive regulation of fertilization	IMP	J:250814
Biological Process	GO:0060903	positive regulation of meiosis I	IMP	J:102875
Biological Process	GO:0010845	positive regulation of reciprocal meiotic recombination	IBA	J:265628
Biological Process	GO:0010845	positive regulation of reciprocal meiotic recombination	IMP	J:159887
Biological Process	GO:0010845	positive regulation of reciprocal meiotic recombination	ISO	J:73065
Biological Process	GO:0010845	positive regulation of reciprocal meiotic recombination	IMP	J:180577
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:102875
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:102875
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0007283	spermatogenesis	IMP	J:143556